Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons.

By Marjolein Visser, B. Goodpaster, Stephen B. Kritchevsky, Anne B. Newman, M. Nevitt, S. Rubin, Eleanor M. Simonsick, Tamara B. Harris. The journals of gerontology. Series A, Biological sciences and medical sciences, 2005

1,351 citations recorded by the source corpus.

Subfields: Geriatrics and Gerontology, Physical Therapy, Sports Therapy and Rehabilitation, Physiology

View Paper: https://www.semanticscholar.org/paper/b4e90bb4e3958ba17350c967cafd7ee5fddf9b50

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In Geriatrics and Gerontology

In Physical Therapy, Sports Therapy and Rehabilitation

Stephanie A. Studenski

In Physiology

Citations in the corpus

Sarcopenia With Limited Mobility: An International Consensus (2011, background): “One reason for this inconsistency is the infiltration into muscle by fat, which is a powerful predictor of future disability and mortality.(29) This has been designated as sarcopenic obesity, myosteatosis, or the ‘‘fat frail.”
Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle (2010, background): “However, fat accumulation can be seen not only in myopathies but also in severe neurogenic atrophy, type II diabetes, obesity or ageing-related sarcopeni”
The FNIH Sarcopenia Project: Rationale, Study Description, Conference Recommendations, and Final Estimates (2014, background): “entirely consistent, the weight of evidence in communitydwelling older adults suggests that (i) low muscle mass is associated with weakness (3), (ii) weakness (now often referred to as “dynapenia”) (4) is strongly associated with function and disability (5,6), but (iii) low muscle mass alone is weak”
Dynapenia and aging: an update. (2012, background): “M *Visser et al. (2005)-”
Sarcopenia, Dynapenia, and the Impact of Advancing Age on Human Skeletal Muscle Size and Strength; a Quantitative Review (2012, background): “This suggests muscle strength mediates any Frontiers in Physiology | Striated Muscle Physiology July 2012 | Volume 3 | Article 260 | 2 relationship between muscle mass and mobility limitation (Visser et al., 2005).”
Intermuscular Fat: A Review of the Consequences and Causes (2014, background): “There is an increasing amount of evidence linking IMAT with mobility impairment in older adults [25, 27, 29, 30, 42, 43].”
Age-related changes in total and regional fat distribution. (2009, neutral): “generally less than 10%, substantially lower than for intermuscular fat (Szczepaniak et al., 1999; Goodpaster et al., 2000a, 2000b; Visser et al., 2005).”