Estradiol and the developing brain.

By Mark I. McCarthy. Physiological Reviews, 2008

870 citations recorded by the source corpus.

Subfields: Genetics, Immunology, Reproductive Medicine

View Paper: https://www.semanticscholar.org/paper/961f6b04e769ba341afcab0af84d1160483cddd3

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. A. Arnold
2. Mark I. McCarthy
3. G. Gillies
4. S. McArthur
5. T. Bale
6. E. Nestler
7. C. Nemeroff
8. Alan S. Brown

In Immunology

1. A. Arnold
2. G. Gillies
3. S. McArthur
4. Alan S. Brown
5. P. Boksa

In Reproductive Medicine

1. A. Arnold
2. G. Gillies
3. S. McArthur

Citations in the corpus

• Early Life Programming and Neurodevelopmental Disorders (2010, background): “Estrogenic involvement in cell death and cell birth in the developing nervous system is a critical component in programming the sexually dimorphic brain (74,75).”
• The organizational-activational hypothesis as the foundation for a unified theory of sexual differentiation of all mammalian tissues (2009, neutral): “Sex steroids influence the outgrowth of axons and dendrites (Toran-Allerand, 1976), the amount of cell death (Forger, 2006), and regulate the number or type of synapses that a cell makes (Matsumoto et al., 2000; McCarthy, 2008).”
• Estrogen Actions in the Brain and the Basis for Differential Action in Men and Women: A Case for Sex-Specific Medicines (2010, background): “These are thoroughly reviewed elsewhere (McCarthy and Konkle, 2005; Wilson and Davies, 2007; McCarthy, 2008) and are of particular interest not only for understanding the actions of estrogens in the developing brain but also for possibly providing clues about estrogenic actions in the injured…”
• Brain On Stress: Vulnerability and Plasticity of the Prefrontal Cortex Over the Life Course (2013, neutral): “…many other subtle sex differences exist throughout the brain, since gonadal steroid receptors and actions via genomic and nongenomic mechanisms are widespread (McEwen and Milner, 2007) and sexual differentiation early in life affects many aspects of brain function (Cahill, 2006; McCarthy, 2008).”
• Prenatal environmental exposures, epigenetics, and disease (2011, neutral): “Experimental evidence ndicates that gestational exposure to environmentally relevant oses of BPA abrogates sexual dimorphism in brain structure and ehavior anddisrupts cognition, social behaviors, andother aspects f brain function [141–143].”
• Reframing sexual differentiation of the brain (2011, background): “Parallel hormonal effects on diverse pathways and circuits The permanent differentiating (organizational) effects of testosterone in the pre- or postnatal brain are often caused by estradiol, a major brain metabolite of testosterone (for a review, see ref”