Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20.
By Y. Ishigaki, Xiaojie Li, G. Serin, L. Maquat. Cell, 2001
616 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/b1e94b41c06ef181f7d624c241ab48a195bf6b55
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In Molecular Biology
Citations in the corpus
- Upstream and downstream of mTOR. (2004, background): “2000), which reportedly functions during the initial round of translation of each mRNA (Ishigaki et al. 2001).”
- Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function. (2007, background): “Initial data revealed that PTC-containing CBP80:CBP20-bound -globin mRNA and PTC-containing eIF4E-bound -globin mRNA are reduced to the same percentage of, respectively, PTC-free CBP80:CBP20-bound -globin mRNA and PTC-free eIF4E-bound -globin mRNA (Ishigaki et al. 2001).”
- Cytoplasmic foci are sites of mRNA decay in human cells (2004, background): “Therefore, it is currently believed that NMD occurs during a pioneering round of translation once the newly synthesized mRNAs reach the cytoplasm after export through the nuclear pore complex, thus, being closely associated with the nucleus (Ishigaki et al., 2001).”