Calcium plus vitamin D supplementation and the risk of colorectal cancer.

By J. Wactawski‐Wende, J. Kotchen, G. Anderson, A. Assaf, R. Brunner, M. O'sullivan, K. Margolis, J. Ockene, L. Phillips, L. Pottern and 37 more. New England Journal of Medicine, 2006

1,006 citations recorded by the source corpus.

Subfields: Nutrition and Dietetics, Oncology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/b1ccd1281751e8dd581b7299431d821f291c19db

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In Nutrition and Dietetics

In Oncology

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Citations in the corpus

Vitamin D for Health: A Global Perspective (2013, positive): “A good example is the WHI.(129) More than 50% of participants in the WHI admitted not taking their calcium and vitaminDdaily, and blood concentrations of 25(OH)Dwere often notmeasured at baseline or at study end.”
American Cancer Society Guideline for Diet and Physical Activity for cancer prevention. (2020, neutral): “10 However, evidence from RCTs for the prevention of colorectal adenomas 103 or cancer 104 have not supported an association.”
Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. (2006, result): “Findings from the WHI appear to contrast with the epidemiologic data described in this review (121).”
Nonclassic actions of vitamin D. (2009, methodology): “A recent report from the Women’s Health Initiative failed to find a reduction in colon cancer in women receiving 400 IU vitamin D plus 1000 mg calcium (101), although this study has been criticized for using too low a dose of vitamin D, poor compliance, and failure to control for vitamin D and calci”
Colorectal Cancer and Nutrition (2019, methodology): “Wactawski-Wende, 2006 [25] Randomized controlled trial USA Daily supplementation of calcium (1000 mg of elemental Ca) with vitamin D (400 IU of Vit D3) for 7 years had no effect on the incidence of CRC among postmenopausal women”
Vitamin D and human health: lessons from vitamin D receptor null mice. (2008, methodology): “In the Women’s Health Initiative (WHI) study, postmenopausal women received calcium (1 g) plus vitamin D (400 IU) or a matching placebo on a daily basis for 7 yr (363).”