Exosomes/microvesicles as a mechanism of cell-to-cell communication.

By G. Camussi, M. Deregibus, S. Bruno, V. Cantaluppi, L. Biancone. Kidney International, 2010

1,162 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/22118db498e28be56cf3711bb5000d038451223d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Y. Lee
2. S. El Andaloussi
3. M. Wood
4. Raymond Schiffelers
5. P. Altevogt
6. P. Vader
7. Sascha Keller

In Molecular Biology

1. P. Vader
2. Y. Lee
3. S. El Andaloussi
4. M. Wood
5. Raymond Schiffelers
6. P. Altevogt
7. Sascha Keller

Citations in the corpus

• Mesenchymal Stem Cell Exosomes Induce Proliferation and Migration of Normal and Chronic Wound Fibroblasts, and Enhance Angiogenesis In Vitro (2015, background): “Exosomes are small membrane-bound vesicles (diameter 30–120 nm), are secreted by a myriad of cells types and found in essentially all biological fluids, and originate from inward budding of late endosomes with resultant multivesicular bodies that are fused with the plasma membrane [20,21].”
• Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy. (2012, background): “These findings led to the hypothesis that microvesicle-mediated therapeutic effects may occur through two different mechanisms involving gene information transfer (7,23,94) (Fig.”
• Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model (2013, background): “EVs may interact with target cells by their inherent surfaceexpressed ligands, transferring surface receptors and delivering proteins, mRNA, and bioactive lipids [8].”
• Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy. (2011, background): “Thus, in addition to being very interesting intercellular signal mediators whose function will be elaborated within the next few years, exosomes appear as promising new tools for the clinical diagnostics and maybe for novel treatment strategies [10,11].”
• Body fluid derived exosomes as a novel template for clinical diagnostics (2011, background): “This can be brought about by uptake of exosomes by target cells or by triggering cell signalling via membrane receptors [8,10].”
• Mesenchymal stem cell-derived extracellular vesicles: novel frontiers in regenerative medicine (2018, background): “These interactions indicate that exosomes possess pivotal roles in cell-to-cell communication and immune modulation in different physiologic and pathologic conditions [13, 15, 17].”
• Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles. (2013, background): “This subpopulation of EVs is believed to contain vesicles somewhat larger in size than exosomes (50–1000 nm) and is usually termed ‘microvesicles’ [1].”