Progress in manipulating ascorbic acid biosynthesis and accumulation in plants

By T. Ishikawa, J. Dowdle, N. Smirnoff. 2006

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Antioxidants and Antioxidant Enzymes in Higher Plants (2018, background): “In spite of the nutritional importance of ascorbate to humans, the ascorbate biosynthesis pathway in plants was elucidated only a decade ago (Smirnoff 2000a, b; Smirnoff and Wheeler 2000; Ishikawa et al. 2006a).”
Redox homeostasis in plants under abiotic stress: role of electron carriers, energy metabolism mediators and proteinaceous thiols (2015, background): “Thus, it regulates defense/stress signaling and cell death pathways under oxidative stress (Ishikawa et al., 2009; Jambunathan et al., 2010).”
Genotypic differences in some physiological parameters symptomatic for oxidative stress under moderate drought in tomato plants. (2010, background): “This regeneration involves the enzymes MDHAR, DHAR, and GR, which are found in most cell compartments [67].”
Biofortification of crops with seven mineral elements often lacking in human diets--iron, zinc, copper, calcium, magnesium, selenium and iodine. (2009, background): “In addition to genotypic effects, ascorbate concentrations in plant tissues are affected by other factors such as developmental stage, time of day, and growth environment (Smirnoff et al., 2001; Ishikawa et al., 2006; Smith et al., 2007).”