Adaptation of core mechanisms to generate cell polarity

By W. Nelson. Nature, 2003

746 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/afa69a064db99c19d9ce614c88ff8a6fe06de5be

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Citations in the corpus

Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation (2004, background): “Epithelial junctions in Drosophila and other organisms consist of a core E-cadherin/β-catenin/α-catenin complex (the adherens junctions”
Cdc42 - the centre of polarity (2004, background): “…further enhanced by the recruitment of a third complex of proteins, containing Crumbs Journal of Cell Science 117 (8) A Migrating fibroblast B Cytotoxic T cell 1297Cdc42 and polarity (Crb), Discs-lost (Dlt) and Stardust (Sdt), to a site apical to the adherens junctions (reviewed by Nelson, 2003).”
From cells to organs: building polarized tissue (2008, background): “Cell polarity involves the asymmetric organization of most of the physical aspects of the cell, including the cell surface, intracellular organelles and the cytoskeleto”
Tight junctions/adherens junctions: basic structure and function. (2007, background): “Studies in Drosophila made the important observation that junction formation is functionally coupled to the establishment of polarity (Nelson, 2003).”
Stochastic mechano-chemical kinetics of molecular motors: A multidisciplinary enterprise from a physicist’s perspective (2012, background): “Establishment, as well as the subsequent maintenance, of cell polarity depend, at least partly, on the dynamic assembly of the cytoskeletal filaments and the motor-driven transport that they support [1002, 1003, 1004, 1005].”
α-Catenin as a tension transducer that induces adherens junction development (2010, neutral): “dtd" [ ]> AJs are associated with actin filaments and are essential for cell recognition and for the maintenance and morphogenesis of epithelial cell sheet”
Organization of vesicular trafficking in epithelia (2005, background): “Recent work has provided fascinating details of their complex interactions and roles in epithelial morphogenesi”