Potential for primary prevention of Alzheimer's disease: an analysis of population-based data.

By S. Norton, F. Matthews, D. Barnes, Kristine Yaffe, Carol Brayne. Lancet Neurology, 2014

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How researchers see this paper

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The Epidemiology of Alzheimer's Disease Modifiable Risk Factors and Prevention (2021, background): “In fact, one-third of AD cases worldwide are attributable to underlying modifiable risk factors (4), which might modulate an individual’s risk of developing AD.”
An Atlas of Genetic Correlations across Human Diseases and Traits (2015, neutral): “[37]: we estimate a statistically significant negative genetic correlation between college and Alzheimer’s disease, which agrees with epidemiological results [38, 39].”
Preclinical Alzheimer’s disease: Definition, natural history, and diagnostic criteria (2016, background): “, different strains of Aß [14,15]; mixed pathology [especially in elderly subjects] [16]; different genetic backgrounds [17–19]; and different relevant risk factors of AD [20]).”
Recent global trends in the prevalence and incidence of dementia, and survival with dementia (2016, background): “In previous modelling exercises, researchers have sought to predict what might happen to the future prevalence of dementia, given our best estimates of risk associations and possible changes in those risk factor profiles over time [8, 50].”