Markers of DNA repair and susceptibility to cancer in humans: an epidemiologic review.

By M. Berwick, P. Vineis. Journal of the National Cancer Institute, 2000

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Deciphering Signatures of Mutational Processes Operative in Human Cancer (2013, background): “The cell employs repair mechanisms that protect the integrity of the genetic code by alleviating and correcting the effects of exogenous and endogenous mutagens (Berwick and Vineis, 2000).”
Cancer epidemiology in the last century and the next decade (2001, background): “Assays for defective DNA repair correlate consistently with substantially increased susceptibilit”
Role of oxidative stress and DNA damage in human carcinogenesis. (2011, background): “Although no knowledge of a definitemechanism exists on the occurrence of elevated DNA damage in the presence of cancerous cells or a tumor in the organism usually referred as ‘reverse-causation’ effect initiated by tumor growth [92], all the above discussed mechanisms of deficient DNA repair and/or ”