Biologic properties of mesenchymal stem cells derived from bone marrow and adipose tissue

By R. Izadpanah, Cynthia B. Trygg, Bindiya Patel, C. Kriedt, J. Dufour, J. Gimble, B. Bunnell. Journal of Cellular Biochemistry, 2006

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Safety and Immunological Effects of Mesenchymal Stem Cell Transplantation in Patients With Multiple Sclerosis and Amyotrophic Lateral Sclerosis (2010, background): “The use of bone marrow–derived stem cells offers several practical advantages: (1) MSCs can be obtained readily and safely from adult bone marrow, even from patients with advanced disease; (2) MSCs, which are normally present in small concentrations in the bone marrow compartment, can be enriched an”
Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation (2007, positive): “MSCs from a variety of mammalian species also express the embryonic stem cell gene markers oct-4, sox-2, and rex-1, among others [25].”
Identification of white adipocyte progenitor cells in vivo. (2008, background): “Although previous studies have shown that adipose tissue stromal cells can differentiate in vitro after several passages (Boquest et al., 2005; Izadpanah et al., 2006; Lee et al., 2004; Wagner et al., 2005), cells isolated in this manner were only able to produce fat pads in vivo when they were…”
Same or Not the Same? Comparison of Adipose Tissue-Derived Versus Bone Marrow-Derived Mesenchymal Stem and Stromal Cells (2012, positive): “Several studies clearly demonstrated that there are some differences in the global transcriptomic and proteomic profiles of BM-MSCs and ASCs [132,145,163,164].”