Evolution and transmission of stable CTL escape mutations in HIV infection

By P. Goulder, C. Brander, Yanhua Tang, C. Tremblay, R. Colbert, M. Addo, E. Rosenberg, T. Nguyen, R. Allen, A. Trocha and 9 more. Nature, 2001

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Comprehensive Epitope Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses Directed against the Entire Expressed HIV-1 Genome Demonstrate Broadly Directed Responses, but No Correlation to Viral Load (2003, background): “The selective immune pressure mediated by CD8 T cells on the viral genome has been further supported by studies demonstrating viral escape from CD8 -cytotoxic T-cell (CTL)-mediated immune pressure in HIV-1 and SIV infection (3, 9, 14, 23, 24, 40).”
Evidence of HIV-1 Adaptation to HLA-Restricted Immune Responses at a Population Level (2002, background): “Selection for escaped HLA-restricted CTL epitopes has been seen in a mother to infant study and has implications for population escape.(894) In EBV, a polymorphism that abrogates binding of an HLA-A11 epitope has been seen at a population level in the local strain found in”