The gut microbiota at the intersection of diet and human health
By C. Gentile, T. Weir. Science, 2018
849 citations recorded by the source corpus.
Diet affects multiple facets of human health and is inextricably linked to chronic metabolic conditions such as obesity, type 2 diabetes, and cardiovascular disease. Dietary nutrients are essential not only for human health but also for the health and survival of the trillions of microbes that reside within the human intestines. Diet is a key component of the relationship between humans and their microbial residents; gut microbes use ingested nutrients for fundamental biological processes, and the metabolic outputs of those processes may have important impacts on human physiology. Studies in humans and animal models are beginning to unravel the underpinnings of this relationship, and increasing evidence suggests that it may underlie some of the broader effects of diet on human health and disease.
Subfields: Molecular Biology, Physiology, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/ac507cbbe7a754b045b23246e47f38163803bfdb
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Citations in the corpus
- The Controversial Role of Human Gut Lachnospiraceae (2020, background): “GI microbes produce several bioactive compounds which can influence the physiology of the host [6,7]; some, like vitamins, are beneficial [8], whilst others are toxic [9].”
- Gut Microbiome: Profound Implications for Diet and Disease (2019, background): “The role of diet in shaping gut microbiota, host metabolism, and lipid homeostasis is changing our view of the steps a person can take to make improvements in their systemic health [10,315].”
- Effect of Diet on the Gut Microbiota: Rethinking Intervention Duration (2019, background): “This state has often been attributed to a high-fat diet, though a mouse study demonstrated that microbial changes leading to this detrimental state were induced by a lack of fermentable fibre rather than dietary fat content [97,98].”