Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus.

By K. Hancock, V. Veguilla, Xiuhua Lu, W. Zhong, Eboneé N. Butler, Hong Sun, Feng Liu, Li-bo Dong, Joshua R DeVos, P. Gargiullo and 4 more. New England Journal of Medicine, 2009

1,300 citations recorded by the source corpus.

Subfields: Epidemiology, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/abbbb194a5f0509fcc723fa95ba75c48b0b73a3f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. F. Krammer
2. A. García‐Sastre
3. P. Palese
4. R. Medina
5. Ian A. Wilson
6. Rafi Ahmed
7. A. Varki
8. J. Taubenberger

In Infectious Diseases

1. P. Palese
2. Ian A. Wilson
3. Rafi Ahmed
4. Kwok-Yung Yuen
5. F. Krammer

Citations in the corpus

• Convalescent Plasma Treatment Reduced Mortality in Patients With Severe Pandemic Influenza A (H1N1) 2009 Virus Infection (2011, background): “This phenomenon was attributed to the absence of preexisting cross-reactive antibodies against this novel virus in patients born after 1950 [11].”
• Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans (2014, background): “Before the emergence of the 2009 pH1N1 virus, the vast majority of young adults who constitute the various cohorts examined in the present study did not have any detectable HAI titers against this virus (26).”
• Influenza A viruses: new research developments (2011, background): “The sera of elderly individuals were found to contain cross-reactive antibodies to the novel strai”
• Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals (2020, neutral): “The frequent availability of crossreactive memory T cell responses might have been one factor contributing to the lesser severity of the H1N1 flu pandemic (Hancock et al., 2009).”
• Structural basis of pre-existing immunity to the 2009 H1N1 pandemic influenza virus (2010, background): “And unlike seasonal flu that usually affects the elderly most severely, swine flu has been primarily targeting people under the age of 65, implying some age-related pre-existing immunity (2, 3).”
• Immune history profoundly affects broadly protective B cell responses to influenza (2015, positive): “Exposure or vaccination with the antigenically similar NJ1976 strain has also been linked to higher Cal09 preexisting serological levels and with generating a more HA head–specific response upon vaccination with Cal09 (29, 31).”