Reciprocal Association of C-Reactive Protein With Adiponectin in Blood Stream and Adipose Tissue

By N. Ouchi, S. Kihara, T. Funahashi, Tadashi Nakamura, M. Nishida, M. Kumada, Y. Okamoto, K. Ohashi, H. Nagaretani, K. Kishida and 5 more. Circulation, 2003

838 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Epidemiology, Immunology

View Paper: https://www.semanticscholar.org/paper/abad8ace3c0f955ce3085d4ab013ab1067a6c223

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. K. Walsh
2. N. Ouchi
3. P. Trayhurn
4. Haiming Cao
5. H. Fang
6. R. L. Judd

In Epidemiology

1. K. Walsh
2. N. Ouchi
3. T. Funahashi
4. P. Trayhurn
5. S. Kihara
6. I. Wood
7. H. Fang
8. R. L. Judd

In Immunology

1. I. Wood
2. P. Trayhurn
3. H. Fang
4. R. L. Judd

Citations in the corpus

• Adiponectin Regulation and Function (2018, neutral): “In humans with coronary artery disease (CAD), inverse associations between plasma and adipose tissue levels of adiponectin and C-reactive protein (CRP), an acute-phase marker of inflammation, have been observed (235).”
• Adipocytokines in Obesity and Metabolic Disease (2014, neutral): “Low levels of plasma adiponectin are associated with C-reactive protein in humans (Ouchi et al. 2003).”
• Adiponectin: action, regulation and association to insulin sensitivity (2005, background): “Adiponectin has various biological functions including insulin sensitizing (27), anti-atherogenic (45), antiinflammatory (49), anti-angiogenic and anti-tumour functions (50).”
• Obesity and Cancer: The Role of Dysfunctional Adipose Tissue (2009, background): “Adiponectin, an adipokine that is exclusively derived from adipocytes, has significant antiinflammatory and insulin-sensitizing effects (62, 63).”
• Noninvasive Markers in the Assessment of Intestinal Inflammation in Inflammatory Bowel Diseases: Performance of Fecal Lactoferrin, Calprotectin, and PMN-Elastase, CRP, and Clinical Indices (2008, background): “Furthermore, it is possible that the sensitivity of CRP might be improved by using a highly sensitive assay for predicting active IBD, as is the case in coronary artery disease (50).”
• Adipokines: inflammation and the pleiotropic role of white adipose tissue (2004, background): “There is evidence from a study using real-time PCR that the gene encoding CRP is expressed in adipose tissue, an inverse correlation between the levels of the mRNA for CRP and adiponectin being apparent (Ouchi et al. 2003).”
• Obesity and inflammation: the linking mechanism and the complications (2016, background): “[105] evaluated the levels typically ranging from 3–30 μg/ml, in normal human subjects.”
• Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms (2005, background): “and are inversely correlated with cardiovascular risk factors including hyperlipidemia, blood pressure and C-reactive protein (CRP) level”