Effects of Chronic Fluoxetine in Animal Models of Anxiety and Depression

By S. Dulawa, K. A. Holick, Brigitta B. Gundersen, R. Hen. Neuropsychopharmacology, 2004

693 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Cellular and Molecular Neuroscience, Social Psychology

View Paper: https://www.semanticscholar.org/paper/ab6d0531d328da569669c1acd8fc54279797ba62

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. Todd D. Gould
2. B. Petit-Demoulière
3. R. Hen
4. H. Schmidt
5. M. Bourin
6. R. Duman
7. Amar Sahay
8. F. Chenu

In Cellular and Molecular Neuroscience

1. R. Hen
2. H. Schmidt
3. Amar Sahay
4. R. Duman
5. Todd D. Gould
6. A. Dranovsky
7. Alexis S. Hill
8. B. Petit-Demoulière

In Social Psychology

1. B. Petit-Demoulière
2. R. Hen
3. H. Schmidt
4. M. Bourin
5. R. Duman
6. Amar Sahay
7. F. Chenu
8. A. Dranovsky

Citations in the corpus

• Forced swimming test in mice: a review of antidepressant activity (2004, methodology): “It showed several differences between chronic and subchronic treatment of a SSRI, fluoxetine, in the FST with BALB/c mice weighting 25–35 g (Dulawa et al. 2004).”
• Mood and anxiety related phenotypes in mice : characterization using behavioral tests (2009, background): “Acute versus chronic administration X (25)”
• Model organisms: The ascent of mouse: advances in modelling human depression and anxiety (2005, neutral): “That said, several recent studies have shown effects of antidepressants in these tests after chronic treatment at much lower doses than those needed to induce effects after short-term treatmen”
• Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish (2009, result): “Behavioral and physiological data from this study agree strongly with that seen in previously published in rodent studies showing that chronic exposure to fluoxetine reduces anxiety [43,44], corticosterone responses (mice [44]) and HPA sensitivity (rats [45,46]).”
• Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors (2015, background): “…effects of chronic CORT administration in different tests than observed here (David et al, 2009), we note that different strains of mice often display inconsistent behavioral phenotypes and responses to various stress models and drugs (Dulawa et al, 2004; Razzoli et al, 2011; Yalcin et al, 2008).”
• The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior (2007, background): “(NIH) paradigm (Dulawa et al., 2004), have been used to study the biological mechanisms underlying the behavioral effects of chronic antidepressant administration.”
• BEHAVIORAL EFFECTS OF FLUOXETINE IN AN ANIMAL MODEL OF ANXIETY/DEPRESSION ARE MEDIATED BY BOTH NEUROGENESIS-DEPENDENT AND INDEPENDENT MECHANISMS (2009, methodology): “Behavioral Testing Open Field This test was performed as described previously (Dulawa et al., 2004).”
• Hippocampal neurogenesis: regulation by stress and antidepressants. (2006, background): “Out of these conflict-based tests, open field, novelty-induced hypophagia, and novelty-suppressed feeding were all shown to have a response specific to chronic antidepressant treatment (Bodnoff et al 1988; Dulawa et al 2004; Merali et al 2003; Santarelli et al 2003).”