Coronavirus Infections-More Than Just the Common Cold.

By Catharine I. Paules, Hilary D. Marston, A. Fauci. Journal of the American Medical Association (JAMA), 2020

1,880 citations recorded by the source corpus.

Human coronaviruses (HCoVs) have long been considered inconsequential pathogens, causing the “common cold” in otherwise healthy people. However, in the 21st century, 2 highly pathogenic HCoVs—severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV)—emerged from animal reservoirs to cause global epidemics with alarming morbidity and mortality. In December 2019, yet another pathogenic HCoV, 2019 novel coronavirus (2019-nCoV), was recognized in Wuhan, China, and has caused serious illness and death. The ultimate scope and effect of this outbreak is unclear at present as the situation is rapidly evolving. Coronaviruses are large, enveloped, positivestrand RNA viruses that can be divided into 4 genera: alpha, beta, delta, and gamma, of which alpha and beta CoVs are known to infect humans.1 Four HCoVs (HCoV 229E, NL63, OC43, and HKU1) are endemic globally and account for 10% to 30% of upper respiratory tract infections in adults. Coronaviruses are ecologically diverse with the greatest variety seen in bats, suggesting that they are the reservoirs for many of these viruses.2 Peridomestic mammals may serve as intermediate hosts, facilitating recombination and mutation events with expansion of genetic diversity.

Subfields: Economics and Econometrics, Modeling and Simulation, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/ab390f10332f80ac78e43338637399325d53f1c8

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Citations in the corpus

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment (2020, background): “Severe Acute Respiratory Syndrome Corona Virus (SARS-CoV) and the Middle East Respiratory Syndrome Corona Virus (MERS-CoV) [1].”
The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020 (2020, background): “The early days of the outbreak have been reminiscent of SARS and MERS, and indeed, the discovery that the causative agent was a closely-related, never-before-described coronavirus predicted potential for nosocomial transmission and so-called “superspreader” events (8).”
False-negative results of initial RT-PCR assays for COVID-19: A systematic review (2020, background): “84 Although most of the cases present mild symptoms, some cases have developed pneumonia, 85 severe respiratory diseases, kidney failure, and even death (7-9).”
Interleukin‐6 in Covid‐19: A systematic review and meta‐analysis (2020, background): “Causing a febrile respiratory illness known as coronavirus disease 2019 (Covid-19), this is the third zoonotic coronavirus to infect humans in the past two decades.(3) Compared to its predecessors, SARS-CoV-2 has demonstrated rapid capacity for dissemination, having infected several million patients”
Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China (2020, background): “COVID-19, similarly to SARS, is a beta-coronavirus that can be spread to humans through intermediate hosts such as bats [5], though the actual route of transmission is still debatable.”
The deadly coronaviruses: The 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China (2020, neutral): “Fifteen health care workers in a Wuhan hospital were infected while caring for patients with confirmed or suspected infection [65,66].”
Risk and Financial Management of COVID-19 in Business, Economics and Finance (2020, methodology): “In a detailed and informative paper, Sethuraman et al. (2020) interpreted two commonly used diagnostic tests of COVID-19, the results of which can and do vary over time.”
Epidemiology of COVID-19 Among Children in China (2020, background): “Four HCoVs (HCoV 229E, NL63, OC43, and HKU1) are endemic globally and account for 10% to 30% of upper respiratory tract infections in adults.(15) Although HCoVs have long been regarded as inconsequential pathogens because of their mild phenotypes in humans, in the early 21st century, 2 large-scale e”
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia (2020, background): “R 0 of SARS was estimated to be around 3,(12) and SARS outbreaks were successfully controlled by isolation of patients and careful infection control.(13) In the case of NCIP, challenges to control include the apparent presence of many mild infections(14) and limited resources for isolation of cases ”
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2): An Update (2020, background): “Peri-domestic mammals can also serve as intermediate hosts, facilitating recombination, mutation, and genetic variations [1,25].”
Covid-19 pandemic and online learning: the challenges and opportunities (2020, background): “Clinical analysis results of the virus showed person-to-person transmission (Li et al., 2020; Paules et al., 2020; Wang, Cheng, et al., 2020).”
Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis (2020, background): “Preparedness at different levels, facing a new clinical disease, demands efforts in epidemiological, diagnostic, therapeutic, and preventive fields during a potential pandemic [46], that threatens to spread to new territories (> 115) and areas with the risk of epidemics.”
Airborne Transmission Route of COVID-19: Why 2 Meters/6 Feet of Inter-Personal Distance Could Not Be Enough (2020, background): “(2020) recently pointed out that the airborne transmission of SARS-COV-2 may also occur besides close distance contacts [3].”