Activation‐induced cell death in T cells

By Douglas R. Green, N. Droin, M. Pinkoski. Immunological Reviews, 2003

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The Role of Selenium in Inflammation and Immunity: From Molecular Mechanisms to Therapeutic Opportunities (2012, background): “This process is termed activation-induced cell death (AICD), and antioxidants have been shown to inhibit AICD in T cells (89).”
IL-2, Regulatory T Cells, and Tolerance (2004, background): “Other gene products that appear to distinguish (albeit imperfectly) CD4 CD25 Tregs from conventional, activated CD4 T cells include the cell surface receptor glucocorticoid-induced TNFR and the transcription factor FoxP3 (55–57).”
NetPath: a public resource of curated signal transduction pathways (2010, background): “In contrast to its proliferative effects, IL-2 also has potent activity in a process known as activation-induced cell death [33].”
Life and death in peripheral T cells (2007, background): “Some findings suggest that TNF is involved in the late phase of AIC”