NetPath: a public resource of curated signal transduction pathways
By K. Kandasamy, S. Mohan, Rajesh Raju, Shivakumar Keerthikumar, G. S. S. Kumar, A. Venugopal, Deepthi Telikicherla, J. Navarro, Suresh Mathivanan, C. Pecquet and 30 more. Genome Biology, 2010
483 citations recorded by the source corpus.
We have developed NetPath as a resource of curated human signaling pathways. As an initial step, NetPath provides detailed maps of a number of immune signaling pathways, which include approximately 1,600 reactions annotated from the literature and more than 2,800 instances of transcriptionally regulated genes - all linked to over 5,500 published articles. We anticipate NetPath to become a consolidated resource for human signaling pathways that should enable systems biology approaches.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/b99e9a1a677806d3f0784118ac8bcfd898feed58
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Citations in the corpus
- Structure and dynamics of molecular networks: A novel paradigm of drug discovery: A comprehensive review (2012, background): “…Croft et al., 2011 NCI Nature–Pathway Interaction Database http://pid.nci.nih.gov Schaefer et al., 2009 NetPath http://netpath.org Kandasamy et al., 2010 JASPAR Transcription factor–transcription factor binding information http://jaspar.genereg.net Portales-Casamar et al.,…”
- Systems Pharmacology: Network Analysis to Identify Multiscale Mechanisms of Drug Action (2012, background): “…genes/proteins involved in these processes can be identified through the use of databases such as the Kyoto Encyclopedia of Genes and Genomes (KEGG) (52), the Gene Ontology project (53), and Reactome (54), or the list may be manually curated on the basis of the physiology of interest (16, 55).”
- WikiPathways: connecting communities (2020, background): “While only 6 out of 639 pathways have not been updated yet, 14 pathways have >100 revisions including the ‘Integrated Breast Cancer Pathway’ (WP1984, 445 revisions, 14 curators, (10)), the ‘Aryl Hydrocarbon Receptor’ pathway from NetPath (WP2586, 256 revisions, 9 curators, (11,12)), and the ‘Seleniu”
- Proteomics: Technologies and Their Applications. (2017, methodology): “Moreover, databases such as Netpath have been developed, which involve the pathways active in cancer that are helpful for the identification of proteins relevant for a cancer type (148).”
- Plasma Proteome Database as a resource for proteomics research: 2014 update (2013, background): “In addition to documentation of plasma proteins and peptide information, for each protein in PPD, we have provided external links to Human Protein Reference Database (HPRD) (30), NetPath (31), Entrez Gene (32) and UniProt (33) (Figure 1).”