Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster.

By T. Boettger, Nadine Beetz, S. Kostin, J. Schneider, M. Krüger, L. Hein, Thomas Braun. Journal of Clinical Investigation, 2009

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MicroRNAs in development and disease. (2011, background): “It is induced by platelet-derived growth factor (PDGF), which is known to stimulate VSMC switching and proliferation during angiogenesis and neointimal formation (133, 378).”
Linking actin dynamics and gene transcription to drive cellular motile functions (2010, positive): “miR-145 knockdown in cultured cells was reported to block smooth muscle gene activation by myocardin, pointing to this miRNA as an essential cofactor of myocardi”
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs (2012, background): “miRNAs also regulate SMC functions, and, in particular, the cluster comprising miR-143 and miR-145 (miR-143/145) has been described to be of crucial importance for proper SMC functio”
MicroRNAs in stress signaling and human disease (2012, background): “However, contractility of the blood vessels of these mice is compromised, suggesting a subtle shift toward a less differentiated phenotype (Boettger et al., 2009).”