Faculty Opinions recommendation of Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction.
By Kent C. Berridge. 2008
216 citations recorded by the source corpus.
View Paper: https://www.semanticscholar.org/paper/aa754d19d2910aee33ef25bcf2dcc55b8a93469f
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
- Nora D. Volkow
- G. Koob
- Gene-Jack Wang
- Reinout W. Wiers
- P. Kenny
- J. S. Fowler
- M. Morales
- Kent C. Berridge
Citations in the corpus
- Go and no-go learning in reward and punishment: Interactions between affect and effect (2012, background): “…omission, since the interaction between action and valence could boost, or indeed prevent learning altogether, and since the neural substrates of acquisition and maintenance could be quite different — as indeed has been claimed for action learning (Atallah et al., 2007; Everitt et al., 2008).”
- Goals and Habits in the Brain (2013, unknown): “One influential proposal is that a protracted exposure to addictive drugs recruits dopamine-dependent striato-nigro-striatal ascending spirals (Haber et al., 2000; Joel and Weiner, 2000) from the nucleus accumbens to more dorsal regions of the striatum (Everitt et al., 2008).”
- Neurocircuitry of Addiction (2009, background): “These results suggest that the dorsal striatum may have a minor role in the acute reinforcing effects of psychostimulant drugs but a key role in the transition to compulsive use (Everitt et al, 2008).”
- The Brain on Drugs: From Reward to Addiction. (2015, background): “Specifically, studies in rodents and non-human primates have found reduced levels of D2R in the striatum, including in the NAc, upon chronic drug exposures, as well as in animals with a propensity to self-administer drugs (Everitt et al., 2008).”
- The Neuroscience of Drug Reward and Addiction. (2019, unknown): “…activity (marker of brain function) in frontal cortical regions and inversely associated with the sensitivity to the rewarding effects of psychostimulant drugs (102, 341, 342), whereas preclinical studies in rodents have shown that D2R upregulation interferes with drug consumption (323, 324).”
- Addiction: Beyond dopamine reward circuitry (2011, background): “associated with impulsivity (32), and low striatal D2R was associated with impulsivity and predicted compulsive cocaine administration in rodents (33).”
- Cognitive Bias Modification and Cognitive Control Training in Addiction and Related Psychopathology (2013, background): “…the result that after prolonged drug use, the addictive behavior can persist despite (lack of) reward or even punishment and can thus develop from an impulsive outcome-focused behavior to compulsive habitual behavior (Everitt et al., 2008; Everitt & Robbins, 2005; Vanderschuren & Everitt, 2004).”
- Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli (2011, unknown): “…may correspond to a transition from limbic and prefrontal cortical control over goal-directed behavior to dorsostriatal control as drug intake becomes compulsive (Haber et al., 2000; Kalivas and Volkow, 2005; Everitt and Robbins, 2005; Everitt et al., 2008; Hyman et al., 2006; Ikemoto, 2007).”
- Reward Mechanisms in Obesity: New Insights and Future Directions (2011, background): “…and decision making (i.e., prefrontal cortex) and in interoceptive processing (insular cortex) have been heavily implicated in drug addiction (Everitt et al., 2008; Fineberg et al., 2010; Koob and Volkow, 2010; Naqvi and Bechara, 2009), yet little is known of their precise role in compulsive…”