Trafficking and proteolytic processing of APP.

By Christian Haass, C. Kaether, G. Thinakaran, Sangram S. Sisodia. Cold Spring Harbor Perspectives in Medicine, 2012

1,069 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Genetics, Physiology

View Paper: https://www.semanticscholar.org/paper/aa30efe9d0fde49ce5940cc9892c4d3872e9ff1d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. J. Long
2. J. Herz
3. G. Bu
4. D. Holtzman

In Genetics

1. J. Long
2. G. Bu
3. D. Holtzman

In Physiology

1. J. Long
2. J. Herz
3. D. Holtzman
4. G. Bu
5. Berislav Zlokovic
6. Martin Citron

Citations in the corpus

• Alzheimer Disease: An Update on Pathobiology and Treatment Strategies (2019, positive): “Aβ is produced by sequential cleavage of β-amyloid precursor protein (APP) by β-secretase and γ-secretase (Figure 2A) (for review see (Haass et al., 2012)).”
• Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. (2012, positive): “Conversely, if APP is retained at the cell surface, it has a greater availability for the cell-surface-localized a-secretase and is cleaved to sAPPa and a minimally toxic peptide p3 (see Haass et al. 2011 for details).”