Circulating MicroRNAs in Patients With Coronary Artery Disease

By S. Fichtlscherer, Salvatore De Rosa, Henrik Fox, T. Schwietz, A. Fischer, C. Liebetrau, Michael A Weber, C. Hamm, Tino Röxe, Marga Müller-Ardogan and 3 more. Circulation Research, 2010

1,253 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a99762eb374d975c5d1427897a5bcbaa2e4310c4

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. E. Olson
2. E. Small
3. Ruben Garcia-Martin
4. R. Kahn
5. Jin Wang
6. S. Sen
7. R. G. Ludwig
8. Jinyun Chen

In Immunology

1. Christian Weber
2. H. Noels

In Molecular Biology

1. E. Olson
2. E. Small
3. Ruben Garcia-Martin
4. Christian Weber
5. R. Kahn
6. Jin Wang
7. S. Sen
8. R. G. Ludwig

Citations in the corpus

• microRNA as Biomarkers and Diagnostics (2016, background): “They are quantitatively altered in certain disease entities, such as myocardial infarction, atherosclerosis, coronary artery disease, heart failure, atrial fibrillation, hypertrophy, and fibrosis (Corsten et al., 2010; Fichtlscherer et al., 2010; da Silva and Silbiger, 2014).”
• The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease (2013, neutral): “In another study, endothelial cells from patients with coronary artery disease (CAD) exhibited higher levels of miR-17 and miR-92a compared with endothelial cells from healthy controls.(93,94) In another study, the miRNA profile of patients with acute coronary syndrome showed an increase of miR-19 c”
• Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study (2015, background): “• Induces IL-6 by binding to TLR8 • Increased in circulation of macaques that developed SIV related CNS disease compared to no disease miR-197 • Inversely associated with myocardial infarction in the Bruneck cohort [43, 44, 50] • Decreased in type 2 Diabetes in the Bruneck cohort • Increased levels ”
• Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease (2019, background): “These include decreased levels of miR-126, miR-17, miR-92a, miR-145 and miR-155; and increased levels of miR-320a, miR-133a and miR-208a (Chen et al., 2015; Fichtlscherer et al., 2010).”
• Atherosclerosis: current pathogenesis and therapeutic options (2011, background): “Recent miRNA profiling studies discovered that circulating levels of vascular-derived miRNAs, including miR-126, were reduced in individuals with CA”
• Pervasive roles of microRNAs in cardiovascular biology (2011, background): “Recently, several miRNAs have been detected in plasma and reported to be diagnostic for heart failure and myocardial infarctio”