Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis

By Lucas Pelkmans, Eugenio Fava, Hannes Grabner, M. Hannus, Bianca Habermann, E. Krausz, Marino Zerial. Nature, 2005

642 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a98c6066f40ee0225333712a45cdf26a617fff95

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Citations in the corpus

PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. (2008, background): “However, caveolin becomes mobile upon cholesterol depletion andalarge-scale screen identifiedkinasesthat when downregulated cause significant changes in caveolin distribution ( Pelkmans et al., 2005 ).”
Large‐scale image‐based screening and profiling of cellular phenotypes (2017, background): “Similarly, several extrinsic-phenotype screens based on genome-wide siRNA libraries also classified the resulting phenotypes into manually defined phenotypic categories (50,52,86).”
Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae (2011, background): “This is consistent with the known role of actin dynamics and various kinases in caveola function (Pelkmans et al., 2005; Pelkmans and Zerial, 2005).”
Hepatitis C Virus Entry Depends on Clathrin-Mediated Endocytosis (2006, background): “It is well established that many regulatory factors have opposite effects on clathrin-mediated and on caveolae/lipid raft-mediated endocytosis ( 38 ).”
Endocytosis, Signaling, and Beyond (2014, background): “…understand in molecular terms the true extent of the impact of endocytosis on cellular homeostasis, and the reciprocal modulation of endocytosis by signaling and metabolic pathways (Pelkmans et al. 2005; Snijder et al. 2009, 2012; Collinet et al. 2010; Lupberger et al. 2011; Mercer et al. 2012).”
Virus Entry: Open Sesame (2006, positive): “RNAi screens similar to those described by Pelkmans et al. (2005) will allow a systematic approach to these questions with the possibility that specific routes can be defined by the requirement for a unique set of genes and their encoded proteins.”
The multiple faces of caveolae (2007, background): “A large-scale RNA interference screen examining the role of specific kinases in caveolar endocytosis has provided key insights into this process and its regulatio”
Pathways of clathrin-independent endocytosis (2007, background): “Indeed, various kinases and signalling molecules have been associated with membrane microdomains and caveolae, and a recent screen of the human kinome identified a total of 80 different kinases that are somehow involved in endocytosis of the caveolar cargo simian virus-40 (SV40”
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. (2006, background): “, 2005) as well as kinases required for clathrinand caveolae-mediated endocytosis (Pelkmans et al., 2005).”