(+)-7-iso-Jasmonoyl-L-isoleucine is the endogenous bioactive jasmonate.

By Sandra Fonseca, Andrea Chini, M. Hamberg, B. Adie, A. Porzel, R. Kramell, O. Miersch, C. Wasternack, R. Solano. Nature Chemical Biology, 2009

933 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/83b1ce5c332c80cdd4ee3d9516d21a7c60b4c247

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Citations in the corpus

Hormonal modulation of plant immunity. (2012, unknown): “Upon synthesis, JA can be readily metabolized to methyl jasmonate (MeJA) through the activity of JA CARBOXYL METHYLTRANSFERASE ( JMT) (Seo et al. 2001) or conjugated to amino acids such as isoleucine via the JA conjugate synthase JAR1 (Staswick & Tiryaki 2004), which results in a biologically highly”
Jasmonate perception by inositol phosphate-potentiated COI1-JAZ co-receptor (2010, background): “From this reconstitution result, we conclude that Ins(1,2,4,5,6)P5 binding is crucial for the JA co-receptor to perceive the hormone with high sensitivity.”
Jasmonate Biosynthesis, Perception and Function in Plant Development and Stress Responses (2013, background): “, free JA, cis-jasmone, MeJA and JA-Ile, are considered to be the major bioactive JA forms in plants (Fonseca et al., 2009).”
The Jasmonate-ZIM-Domain Proteins Interact with the WD-Repeat/bHLH/MYB Complexes to Regulate Jasmonate-Mediated Anthocyanin Accumulation and Trichome Initiation in Arabidopsis thaliana[C][W] (2011, background): “…of the SCFCOI1 complex, contain 12 members and function as negative regulators to repress diverse JA responses, probably by directly inhibiting various transcriptional regulators (Chini et al., 2007; Thines et al., 2007; Yan et al., 2007; Fonseca et al., 2009a; Seo et al., 2011; Song et al., 2011).”
Jasmonates: biosynthesis, perception, signal transduction and action in plant stress response, growth and development. An update to the 2007 review in Annals of Botany. (2013, background): “With the JAZ proteins, however, the first mechanistic explanations were possible on JA perception, including identification of (+)-7-iso-jasmonoyl-L-isoleucine (JA-Ile) as the ligand of a JA receptor (Fonseca et al., 2009).”
The Role of Stress-Responsive Transcription Factors in Modulating Abiotic Stress Tolerance in Plants (2020, background): “JA-Ile is an active form of JA that interacts with JA receptors to promote the JA-dependent stress response [54].”
Growth-defense tradeoffs in plants: a balancing act to optimize fitness. (2014, unknown): “Upon wounding or pathogen attack, JA-Ile is rapidly synthesized in both local and distal tissues (Staswick and Tiryaki, 2004; Fonseca et al., 2009).”
The Arabidopsis CORONATINE INSENSITIVE1 Protein Is a Jasmonate Receptor[C][W] (2009, background): “However, the JA binding assays in previous studies were performed with crude plant extracts (Thines et al., 2007; Katsir et al., 2008; Melotto et al., 2008) or with partially purified proteins (Fonseca et al., 2009), where COI1 is undoubtedly associated with other proteins that copurified with it.”
Plant Defense against Insect Herbivores (2013, background): “Furthermore, the activity was reduced in vitro by increasing the temperature, shifting to an alkaline environment, or through methylation [141].”
Hormone crosstalk in plant disease and defense: more than just jasmonate-salicylate antagonism. (2011, background): “Most JA responses are mediated through the coronatine insensitive 1 (COI1) F-box protein (26, 55, 170, 221); coi1 mutants are more resistant to bacterial pathogens and show elevated SA levels (93).”
The JAZ Proteins: A Crucial Interface in the Jasmonate Signaling Cascade (2011, background): “…in JA perception and signaling has been discussed in many reviews (Balbi and Devoto, 2008; Chico et al., 2008; Katsir et al., 2008a; Kazan and Manners, 2008; Staswick, 2008; Browse, 2009a, 2009b; Chini et al., 2009a; Chung et al., 2009; Fonseca et al., 2009a; Memelink, 2009; Gfeller et al., 2010).”
Jasmonates: biosynthesis, metabolism, and signaling by proteins activating and repressing transcription (2016, background): “(+)-7-iso-JA-Ile is the most bioactive endogenous JA in promoting COI1 interaction with JAZ1, and the JA analog coronatine synthesized by some strains of Pseudomonas syringae is more active than (+)-7-iso-JA-Ile (Fonseca et al., 2009), and can be a potent agonist of the JA receptor complex (Katsir e”
Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, unknown): “The transcript abundance was normalized against peanut Ubiquitin (Luo et al. , 2005) transcript levels.”