Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction

By K. Ozaki, Y. Ohnishi, A. Iida, A. Sekine, R. Yamada, Tatsuhiko Tsunoda, Hiroshi Sato, Hideyuki Sato, M. Hori, Yusuke Nakamura and 1 more. Nature Genetics, 2002

864 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology, Oncology

View Paper: https://www.semanticscholar.org/paper/a740f0d0055af7974b3fc63be5bf307f007438b6

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In Immunology

1. Hakon Hakonarson

In Oncology

1. Julio César Díaz Vera
2. Xin Lai
3. Yujie You
4. Le Zhang
5. Suran Liu
6. Ying Pan
7. Huiru Zheng
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Citations in the corpus

• A review on coronary artery disease, its risk factors, and therapeutics (2019, background): “Lymphotoxin α is another susceptibility gene mediating immune responses and inflammation and has been suspected to be associated with MI (Koch et al., 2001; Ozaki et al., 2002; Yamada et al., 2004).”
• Artificial intelligence in cancer target identification and drug discovery (2022, methodology): “Applications of genomics include fi nding associations between genotype and phenotype 58 , discovering biomarkers for patient strati fi cation 59 , predicting the function of genes 60 and charting biochemically active genomic regions such as transcriptional enhancers 49 .”
• Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus (2008, background): “The multistage strategy for GWASs has an advantage in the effective elimination of a large number of false-positive results and has proved to be successfu”
• Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction (2006, methodology): “The diagnosis of definite myocardial infarction has been previously described (Ohnishi et al. 2000; Ozaki et al. 2002).”
• The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke (2004, background): “Case-control association studies have identified several proinflammatory genes with variants that are associated with either an increased risk of myocardial infarction or a protective effec”
• Genome-wide strategies for detecting multiple loci that influence complex diseases (2005, background): “Initial reports of such studies are appearing in the literatur”