Haplotype tagging for the identification of common disease genes

By G. Johnson, L. Esposito, B. Barratt, Annabel N. Smith, J. Heward, G. D. Genova, H. Ueda, Heather J. Cordell, I. Eaves, Frank Dudbridge and 11 more. Nature Genetics, 2001

1,250 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a6eb8a4da301972c51aae4e8a0f79111929710ea

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Citations in the corpus

Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. (2005, neutral): “Changes in the shading along a haplotype represent ancestral recombination events; these are more likely h h h 1 2 3 to occur between SNPs that are farther apart (e.g., SNPs 2 and 3 or 4 and 5) or that have a higher rate of recombination between them.”
High-resolution haplotype structure in the human genome (2001, neutral): “Once the haplotype blocks are defined, however, it is straightforward to examine a subset of SNPs that uniquely distinguish the common haplotypes in each block (shown elsewhere in this issue”
Impact of selection, mutation rate and genetic drift on human genetic variation. (2003, background): “In addition to satisfying theoretical interests, understanding the heterogeneity of the polymorphism rate is important for the optimisation of the design of association studies aimed at the identification of alleles responsible for human phenotypes (7-10).”
Haplotype blocks and linkage disequilibrium in the human genome (2003, background): “The main haplotypes in each block could be labelled with a small number of 'haplotype-tagging' SNPs, which would provide an efficient mechanism for screening each haplotype-block region for associatio”
Genotype imputation for genome-wide association studies (2010, methodology): “) carry out imputation using methods based on tag SNP approache”
Applications of Linkage Disequilibrium and Association Mapping in Maize (2009, neutral): “In order to maximize the information content of SNPs, a large number of them can be chosen to scan a particular genomic region, and this can be achieved with numerous algorithms available for choosing SNPs (Daly et al. 2001; Johnson et al. 2001; Patil et al. 2001; Gabriel et al. 2002; Ackerman et al”
Genome-wide association studies: theoretical and practical concerns (2005, background): “pkg">tag SNPs (see Online links box)) that capture most of the allelic variation in a regio”
Microsatellite and SNP Markers in Wheat Breeding (2007, background): “org) but at present it is still not clear how efficient the analysis of haplotyopes is for the identification of quantitative traits (Johnson et al., 2001; Foster and Sharp, 2004).”