Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance.
By M. Gómez-Cabrera, Elena Doménech, M. Romagnoli, A. Arduini, C. Borrás, F. Pallardó, J. Sastre, J. Viña. American Journal of Clinical Nutrition, 2008
855 citations recorded by the source corpus.
Subfields: Biochemistry, Nutrition and Dietetics, Rehabilitation
View Paper: https://www.semanticscholar.org/paper/a5ea85cd5b7b3b40b2893bf4d8adfac1c0a41682
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Citations in the corpus
- Exercise is the real polypill. (2013, background): “Interestingly, despite its popularity among westerners for its hypothetical anti-disease/rejuvenating effects, antioxidant supplementation does not mimic, and in fact can reverse, beneficial exercise adaptations (127, 148, 149, 226, 404).”
- Role of ROS and RNS Sources in Physiological and Pathological Conditions (2016, background): “Moreover, notwithstanding conflicting results exist in literature [349], it was reported that antioxidant supplementation attenuates the PGC-1α expression increase due to training [316–318, 350–352].”
- How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis). (2010, background): “Notably, supplementation with ROS-reducing antioxidants inhibits (Gomez-Cabrera et al., 2008; Ristow et al., 2009) the health-promoting effects (Higuchi et al., 1985; Lindsted et al., 1991; Manini et al., 2006; Warburton et al., 2006; Lanza et al., 2008) of physical exercise .”
- Extending life span by increasing oxidative stress. (2011, background): “Moreover, health-promoting effects were demonstrated to be reduced if subjects exposed to physical activity were cotreated with antioxidant supplements [186,243].”
- Antioxidants prevent health-promoting effects of physical exercise in humans (2009, background): “Evidence for this novel concept has been provided in model organisms such as nematodes (15) and rats (17), and the current study would extend the concept of mitohormesis to the amelioration of insulin resistance in humans, suggesting that potential harmful ROS may exert health promoting effects via ”