Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells.

By S. Glennie, Inês Soeiro, P. J. Dyson, E. Lam, F. Dazzi. Blood, 2005

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Mesenchymal stem cells: mechanisms of inflammation. (2011, background): “Several but not all studies suggest that one mechanism to reduce the proliferation of T cells may occur via effects on the cell cycle, particularly in the G1 phase or the G0/G1 transition, which result in the induction of T cell anergy (51).”
Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis (2009, result): “In agreement with our data, BM-MSCs stimulate the production of IL10 by monocytes and DCs.6 25 26 Interestingly, based on the expression of a particular set of chemokine receptors (ie, CCR1, CCR5 and CCR9), which have been involved in cell migration to inflamed tissues, hASCs rapidly and specificall”
Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma (2006, background): “Collectively with other studies demonstrating inhibitory effects on dendritic cells (39) and T cells (40), our fi ndings suggest that MSCs can communicate with a variety of cell types and prevent cellular activation in a contact-dependent manner.”
Mesenchymal Stem Cells: Mechanisms of Immunomodulation and Homing (2010, background): “It has been shown that MSC do not promote T cell apoptosis, but rather induce T cell anergy [ 7, 16 ] .”
Mesenchymal stem cells avoid allogeneic rejection (2005, background): “In addition, removal of MSC from the system only restored IFN-γ production but not T cell proliferation[52].”