Mesenchymal stem cells: mechanisms of inflammation.

By N. Singer, A. Caplan. Annual Review of Pathology, 2011

852 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Comparative Analysis of Human Mesenchymal Stem Cells from Bone Marrow, Adipose Tissue, and Umbilical Cord Blood as Sources of Cell Therapy (2013, positive): “Mechanistic evidence of the benefits of MSCs has been based on their paracrine effect, controlling inflammation or promoting regeneration via soluble factors [19,20].”
Same or Not the Same? Comparison of Adipose Tissue-Derived Versus Bone Marrow-Derived Mesenchymal Stem and Stromal Cells (2012, neutral): “The presence of activated MSCs at sites of inflammation or tissue damage is quite well understood, given that pericytes would be released from their endothelial interactions in vascularized locations; however, the relative number and source of MSCs that are mobilized from either remote or proximate ”
Repair and tissue engineering techniques for articular cartilage (2014, neutral): “55,56 Another beneficial trait is their ability to selectively migrate to diseased tissues and organs, where they have been found to secrete T-cell-suppressive cytokines 57,58 known to be important for allotransplantation and xenotransplantation.”
Extracellular matrix: a dynamic niche component during cancer progression (2012, neutral): “This is an especially important point, as MSCs can exert pleiotropic effects on inflammation (Aggarwal and Pittenger, 2005; Ripoll et al., 2011; Singer and Caplan, 2011).”