Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis

By E. González-Rey, P. Anderson, Manuel A. González, L. Rico, D. Büscher, M. Delgado. Gut, 2009

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Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study (2010, background): “increasing survival.(8) 9 Furthermore, in humans, transplantation of bone marrow (bm) derived MSCs has led to improvement of corticoid refractory graft versus host disease (GvHD), including GvHD of the gut(10) 11 and MSCs obtained from adipose tissue induced healing in complex perianal fistulas in p”
Same or Not the Same? Comparison of Adipose Tissue-Derived Versus Bone Marrow-Derived Mesenchymal Stem and Stromal Cells (2012, neutral): “Full-thickness dermal wound Mouse/ASCs Promotion of dermal wound healing [293] Sepsis Mouse/ASCs Amelioration of sepsis [294] Alergic rhinitis Mouse/ASCs Alleviation of symptoms of alergic rhinitis, inhibition of eosinophilic inflammation [295]”
Antibacterial Effect of Human Mesenchymal Stem Cells Is Mediated in Part from Secretion of the Antimicrobial Peptide LL-37 (2010, background): “5A–5D), reflecting the immunomodulatory properties of MSCs [18–22].”
Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion (2012, background): “Animal models demonstrate that MSC induce the repair of injured organs and ameliorate inflammatory processes (Morigi et al., 2008; Aurich et al., 2009; Gonzalez-Rey et al., 2009; Fisher-Shoval et al., 2012).”