Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells.

By B. Chithrani, A. Ghazani, W. Chan. Nano letters (Print), 2006

4,647 citations recorded by the source corpus.

Subfields: Electronic, Optical and Magnetic Materials, Materials Chemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a3176cbf41ebae1549fb828ebef7596c7fe51a19

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Electronic, Optical and Magnetic Materials

1. L. Dykman
2. Alaaldin M. Alkilany
3. Nikolai G. Khlebtsov
4. C. Murphy
5. W. Chan
6. Alexandre Albanese
7. Ji-Ho Park
8. Nuri Oh

In Materials Chemistry

1. Alaaldin M. Alkilany
2. C. Murphy
3. Nikolai G. Khlebtsov
4. L. Dykman
5. S. Mitragotri
6. W. Chan
7. Joerg Lahann
8. Alexandre Albanese

In Molecular Biology

1. Alaaldin M. Alkilany
2. C. Murphy
3. Triantafyllos Stylianopoulos
4. W. Chan
5. L. Dykman
6. Rakesh K. Jain
7. S. Mitragotri
8. Joerg Lahann

Citations in the corpus

• Fate and Bioavailability of Engineered Nanoparticles in Soils: A Review (2014, background): “Shape (i.e., the aspect ratio) of ENM is also important for endocytosis, increasing aspect ratio decreased the rate of uptake of gold nanomaterials in vitro (Chithrani et al., 2006).”
• Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. (2010, background): “Particle size and surface charge can affect the efficiency and pathway of cellular uptake for liposomes [4], quantum dots [5], polymeric NPs [6,7], gold NPs [8], and silica NPs [2] by influencing the adhesion of the particles and their interaction with cells [9].”
• Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements☆ (2017, background): “Cellular uptake of AuNPs occurs predominantly through receptor-mediated endocytosis (RME), which is an energy-dependent process that is highly influenced by the particle size and shape, as well as the degree of nonspecific adsorption of serum proteins [181,182].”
• Optical properties and biomedical applications of plasmonic nanoparticles (2010, background): “, [249,250] and references therein), Chan et al.”
• Delivering nanomedicine to solid tumors (2010, background): “In addition, researchers have found both experimentally and with the use of mathematical modeling that internalization is maximized for a range of particle sizes”
• Mechanisms of nanotoxicity: Generation of reactive oxygen species (2014, background): “[108] Chithrani BD, Ghazani AA, Chan WC.”