The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews.

By J. Struewing, P. Hartge, S. Wacholder, S. M. Baker, M. Berlin, M. McAdams, Michelle M. Timmerman, L. Brody, Margaret A. Tucker. 1997

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The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Michael A. Newton
2. J. Garber
3. Timothy R. Rebbeck
4. Christina Kendziorski
5. H. Lan
6. M. Daly
7. T. Friebel
8. Michael N. Gould

Citations in the corpus

• Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies. (2003, background): “Another study, based on the family histories of 120 Ashkenazi Jewish volunteers in whom one of three different founder mutations common to this population had been identified, also reported lower penetrance estimates than reports based on multiple-case families (Struewing et al. 1997).”
• Efficacy of bilateral prophylactic mastectomy in BRCA1 and BRCA2 gene mutation carriers. (2001, methodology): “The cumulative penetrances, at 10-year age intervals, were abstracted from (1) and (3) for the high penetrance model and from ( 2 ) for the lower penetrance model.”