Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies.
By A. Antoniou, P. Pharoah, S. Narod, H. Risch, J. Eyfjord, J. Hopper, N. Loman, Hampus Olsson, O. Johannsson, Å. Borg and 23 more. American Journal of Human Genetics, 2003
3,796 citations recorded by the source corpus.
Subfields: Cancer Research, Genetics, Reproductive Medicine
View Paper: https://www.semanticscholar.org/paper/4cddb48206cf42328cac11662d8feaf9bb3698dd
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Citations in the corpus
- 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks (2010, neutral): “Implications for cancer therapy Germline mutations in Brca1 confer susceptibility of developing breast and ovarian cancer with high penetrance (Antoniou et al., 2003).”
- From cancer patient to cancer survivor : lost in transition (2006, background): “Women with BRCA1 and BRCA2 mutations who do not undergo prophylactic surgery have a risk of breast cancer of 45 to 84 percent by age 70 (Ford et al., 1998; Antoniou et al., 2003; King et al., 2003; Easton et al., 2004).”
- Homologous recombination and human health: the roles of BRCA1, BRCA2 and associated proteins (2015, background): “Like BRCA1, BRCA2 mutation carriers are also predisposed to ovarian cancer as well as other tumors at a lower penetrance, such as that of the prostate and pancreas (Ozcelik et al. 1997; Consortium 1999; Antoniou et al. 2003; Edwards et al. 2003; King et al. 2003; van Asperen et al. 2005).”
- The distinctive biology of cancer in adolescents and young adults (2008, background): “Breast cancer at an early age is more likely to be associated with an increased familial risk, especially in women born with BRCA1 mutation”