Autophagy and Aging: The Importance of Maintaining "Clean" Cells
By A. Cuervo, E. Bergamini, U. Brunk, W. Dröge, M. Ffrench, A. Terman. Autophagy, 2005
825 citations recorded by the source corpus.
Subfields: Aging, Epidemiology, Physiology
View Paper: https://www.semanticscholar.org/paper/a18406b6a0a0474b7cdd1a9ffef110fc8e1fff42
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Aging
In Epidemiology
In Physiology
- N. Mizushima
- Brian K. Kennedy
- V. Longo
- D. Klionsky
- M. Hansen
- C. Kenyon
- Luigi Ferrucci
- Eleanor M. Simonsick
Citations in the corpus
- Autophagy is a Protective Mechanism in Normal Cartilage and its Aging-related Loss is Linked with Cell Death and Osteoarthritis (2010, background): “In particular, the effects of oxidative stress on the insulin receptor signaling pathway seem to play a critical role in decreased autophagy in aged organisms (41).”
- New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate (2014, background): “Autophagy is a lysosomal catabolic process that degrades accumulated and unnecessary intracellular materials [17,18,69].”
- A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance and healthspan (2015, background): “The failure to induce autophagy contributes to cellular damage, carcinogenesis, and aging (Cuervo et al., 2005).”
- Protein turnover via autophagy: implications for metabolism. (2007, background): “Many of these aspects of autophagy have recently been the subject of reviews (11, 12, 59, 68, 79, 98, 106).”
- A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans (2008, background): “For instance, dietary restriction stimulates autophagy in old rodents [19-21], and in C.”
- Measuring biological aging in humans: A quest (2019, background): “The repair, recycling, and elimination of damaged macromolecules/ organelles have emerged as key processes in maintaining cell integrity and function (Cuervo et al., 2005; Cuervo, Wong, & MartinezVicente, 2010).”