Variable cytocompatibility of six cell lines with photoinitiators used for polymerizing hydrogels and cell encapsulation.

By Christopher G. Williams, Athar Malik, Tae K. Kim, P. Manson, J. Elisseeff. Biomaterials, 2005

863 citations recorded by the source corpus.

Subfields: Dermatology, Organic Chemistry, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/a0fc7d7f918d8c1e0e2bd632ffd4af877e7f62c8

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In Dermatology

Jason A. Burdick

In Organic Chemistry

In Pulmonary and Respiratory Medicine

Citations in the corpus

A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering. (2012, background): “Cytotoxicity studies of several frequently used UV and visible light initiating systems have been performed [257,258].”
In situ Forming Injectable Hydrogels for Drug Delivery and Wound Repair (2018, positive): “Even so, several other reports have demonstrated that at low photoinitiator concentrations, photocrosslinking allows for encapsulation of many different cell types with minimal cytotoxicity [98,99], but may result in altered gene expression due to the high prevalence of free radicals [100] implying ”
Cell Encapsulation in Biodegradable Hydrogels for Tissue Engineering Applications (2008, positive): “Cytotoxicity of several photoinitiators has also been examined where the initiator chemistry and concentration influenced cell viability, which was found to be dependent on cell division rate.(16,17) In addition to initiator chemistry and concentration, radical concentration and length of exposure t”
The knee meniscus: structure-function, pathophysiology, current repair techniques, and prospects for regeneration (2011, background): “This deficiency may potentially be modulated through increased hydrogel crosslinking, but some crosslinking methods have been shown to affect cytotoxicity and cellular metabolism [196,197].”
Gelatin-Methacryloyl Hydrogels: Towards Biofabrication-Based Tissue Repair (2016, background): “This water-soluble initiator, which dissociates into a benzoyl and ketyl-free radical upon UV light irradiation through an ∝-cleavage reaction [29], has a relatively low cytotoxicity compared with other photoinitiators [30].”
A review of key challenges of electrospun scaffolds for tissue‐engineering applications (2016, background): “Cell tolerance has been observed using a few photo-initiators (Williams et al., 2005).”
Multifunctional chondroitin sulphate for cartilage tissue-biomaterial integration. (2007, background): “A macromer (pregel) solution containing a biocompatible initiato”