Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor.

By S. Maier, Linda R. Watkins. Neuroscience and Biobehavioral Reviews, 2005

713 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Molecular Biology, Social Psychology

View Paper: https://www.semanticscholar.org/paper/a0eb0424476a0d533d4e5c27e3d5e517c6e61a09

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Citations in the corpus

More than a feeling: A unified view of stress measurement for population science (2018, background): “Other work has focused on the degree of controllability that different stressors possess (Maier and Watkins, 2005).”
The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior (2007, background): “Moreover, the role of fear and distractibility in the cognitive effects of LH suggests that this paradigm may be more relevant to anxiety-like behaviors (Maier and Watkins, 2005).”
Stress and Memory: Behavioral Effects and Neurobiological Mechanisms (2007, background): “Convergent evidence indicates that experiencing uncontrollable—as opposed to controllable—stress has deleterious effects on further information processing (Maier and Watkins [24]).”
Perceived Control and the Development of Coping (2010, background): “Careful experimental studies of objective non-contingency have been able to uncover the neurological and hormonal pathways by which it shapes stress responses, and have shown that its deleterious eff ects can be found across a range of mammalian species (Maier & Watkins, 2005 ).”
Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure (2006, background): “In fact, the use of footshock stress helped enable many of the major breakthroughs over the last several decades in the understanding of the neurobiological, cognitive, and behavioral substrates of anxiety and depression; footshock was the stressor used in procedures such as conditioned fear, fear-p”
The roles of the amygdala in the affective regulation of body, brain, and behaviour (2010, background): “5-HT modulates mood, anger, aggression, stress, sleep, body temperature, and metabolism (Grahn, Maswood, McQueen, Watkins, and Maier 1999; Maier and Watkins 2005; Sørensen, Bjorvatn, and Ursin 2000; Nelson and Trainor 2007).6 4.3.”
The habenula: from stress evasion to value-based decision-making (2010, background): “and increases serotonin release in different brain region”
Depression: An Evolutionarily Conserved Mechanism to Terminate Separation Distress? A Review of Aminergic, Peptidergic, and Neural Network Perspectives (2009, background): “…CRF/ ACTH/cortisol system, or, more broadly, perhaps some form of fundamental dysregulation driven by excessive emotional activity of various sorts (Maier & Watkins, 2005), has been consistently implicated in depression, with the most classic early finding being the failure to suppress endogenous…”
The ecology of human fear: survival optimization and the nervous system (2015, background): “…between current and evolutionary environments suggest that fixed systems may be the source of problems (e.g., stress), we further speculate that a side effect of extensive flexibility (e.g., the ability to cognize about future oriented threat) may render humans vulnerable to psychopathology.”
Bonsai Trees in Your Head: How the Pavlovian System Sculpts Goal-Directed Choices by Pruning Decision Trees (2012, background): “interpreted in goal-directed terms [17], depends critically on preand infralimbic cortex in rats [38], and is known to be mediated by serotonin [39].”
“The Biological Effects of Childhood Trauma” (2014, positive): “tioning theory, where animals learn to generalized behaviors based on previous experiences, or reinforcements,(14) and in animal models of learned helplessness, where animals under conditions of uncontrollable shock do not learn escape behaviors and have exaggerated fear responses as well as social ”
Neuroendocrinology of coping styles: towards understanding the biology of individual variation. (2010, positive): “CRF1-mediated inhibition and CRF2-mediated excitation of the dorsal raphe 5-HT system facilitates active and passive coping strategies, respectively [61,89].”