Characterization of human embryonic stem cell lines by the International Stem Cell Initiative
By Oluseun Adewumi, B. Aflatoonian, L. Åhrlund-Richter, M. Amit, P. Andrews, G. Beighton, P. Bello, N. Benvenisty, Lorraine S. Berry, S. Bevan and 75 more. Nature Biotechnology, 2007
1,116 citations recorded by the source corpus.
Subfields: Genetics, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/a0b085851096fb59fa0b3a62ec5704a36decabf6
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In Genetics
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In Molecular Biology
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Citations in the corpus
- Pluripotency: Toward a gold standard for human ES and iPS cells (2009, background): “…expression studies suggest that fully reprogrammed cells represent a developmental stage equivalent to that of ES cells, since they are almost indistinguishable by ChIP on Chip analysis of histone marks (Wernig et al., 2007) and transcriptome microarray (Adewumi et al., 2007; Lowry et al., 2008).”
- Induction of pluripotent stem cells from adult human fibroblasts by defined factors. (2007, background): “RT-PCR showed human iPS cells expressed many undifferentiated ES cell-marker genes (Adewumi et al., 2007), such as OCT3/4, SOX2, NANOG, growth and differentiation factor 3 (GDF3), reduced expression 1 (REX1), fibroblast growth factor 4 (FGF4), embryonic cell-specific gene 1 (ESG1), developmental plu”
- The tumorigenicity of human embryonic and induced pluripotent stem cells (2011, background): “Although HESCs exhibit fairly stable genomic imprinting at early passage”
- Generation of human induced pluripotent stem cells from dermal fibroblasts (2008, background): “13; c, up-regulated by International Stem Cell Consortium (14); d, defined factors to induce pluripotency; fold is Log2.”
- Hydrodynamic stretching of single cells for large population mechanical phenotyping (2012, background): “These markers, including SSEA4, OCT4, and NANOG (36), exhibit significant overlap and variable expression over orders of magnitude when measured with flow cytometry (see SI Text for further discussion).”
- Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human (2014, positive): “Analysis of an independent panel of genes selected by the International Stem Cell Initiative (Adewumi et al., 2007) shows that reset cells and ESC share similar patterns with respect to upregulation of pluripotency regulators and repression of lineage markers (Figure 5B).”