Hyaluronan fragments: an information-rich system.

By R. Stern, A. Asari, K. Sugahara. European Journal of Cell Biology, 2006

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Hyaluronan: A Simple Polysaccharide with Diverse Biological Functions (2013, background): “Given that HABP generally interact with a minimum of 6–10 sugar repeats of HA [63], a single chain of high molecular weight HA can theoretically accommodate in the order of 1000 protein molecules [72].”
Hyaluronic acid: a natural biopolymer with a broad range of biomedical and industrial applications (2006, background): “HA polymers (Stern et al. 2006).”
Macrophage activation by endogenous danger signals (2008, background): “Hyaluronan is a major component of the extracellular matrix (ECM), with a structure of nonsulphated glycosaminoglycan that consists of repeating polymetric disaccharides D-glucuronic acid and N -acetyl glucosamine [61].”
Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications (2011, background): “Many authors have reported and reviewed the numerous unctions of HA and HA fragments in wound healing (Chen & batangelo, 1999; Stern et al., 2006), as well as in tumor growth nd cancer proliferation, during which CD44 cell receptors are overxpressed (Stern, 2008; Sugahara et al.”
Para-inflammation in the aging retina. (2009, background): “Hyaluronan (HA), a major component of the extracellular matrix (ECM), is a non-sulphated glycosaminoglycan that consists of repeating polymetric disaccharides of D-glucoronic acid and N-acetyl glucosamine (Stern et al., 2006).”