Glial Fibrillary Acidic Protein: GFAP-Thirty-One Years (1969–2000)

By L. Eng, R. Ghirnikar, Yuen‐Ling Lee. Neurochemical Research, 2000

1,393 citations recorded by the source corpus.

Subfields: Molecular Biology, Neurology

View Paper: https://www.semanticscholar.org/paper/9f743a8d87f671bf9aefdc1eb9e92042337b48cc

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In Molecular Biology

1. M. Sofroniew
2. M. Pekna
3. M. Pekny
4. Alvaro Pascual-Leone
5. H. Vinters
6. R. Ji
7. C. Nicholson
8. Ed Boyden

In Neurology

1. M. Sofroniew
2. M. Pekny
3. M. Pekna
4. H. Vinters
5. Maiken Nedergaard
6. Y. Ao
7. B. Song
8. T. Berta

Citations in the corpus

• STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury (2008, background): “Intermediate filaments are structural proteins (Eng et al., 2000) and astrocytes exhibit attenuated hypertrophy after forebrain injury in mice with global deletion of GFAP and vimentin (Wilhelmsson et al., 2004).”
• Astrocyte reactivity and reactive astrogliosis: costs and benefits. (2014, background): “Of those, upregulation of glial fibrillary acidic protein (GFAP), the main constituent of astrocyte intermediate filaments (IFs, sometimes also referred to as nanofilaments), has most commonly been used as a hallmark of reactive astrocytes in both human pathology and in experimental studies using va”
• Astrocytes and Brain Injury (2003, background): “Glial fibrillary acidic protein (GFAP) and S-100 (a cytosolic Ca-binding protein) are commonly used as astrocyte markers (Ludwin et al., 1976; Eng et al., 2000).”
• Noninvasive deep brain stimulation via temporally interfering electric fields (2017, positive): “Brain sections were fluores-cently stained with antibodies for the neuronal marker NeuN (Wolf et al., 1996), the apoptotic marker cleaved caspase-3 (D’Amelio et al., 2012), the DNA damage marker g H2AX (Mah et al., 2010), the microglial marker Iba1 (Ito et al., 1998), the astrocyte marker GFAP (Eng e”
• Glia and pain: Is chronic pain a gliopathy? (2013, background): “tions of the protein but not actual changes in protein expression, because of different fixation conditions [15,56].”
• Diffusion in Brain Extracellular Space (2008, positive): “GFAP is the main component of intermediate filaments in astrocytes (95).”
• Astrocytes: biology and pathology (2009, background): “GFAP was first isolated as a protein highly concentrated in old demyelinated plaques from multiple sclerosis patients and was then found to be associated immunohistochemically with reactive astrocytes in such plaques and in other pathological contexts [62, 63].”