The evolution of gene duplications: classifying and distinguishing between models

By Hideki Innan, Fyodor A. Kondrashov. Nature reviews genetics, 2010

1,280 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/9ecb88ccdc4fe8059ef00d9f7c0bb8bbd05b12d0

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Citations in the corpus

Origins, evolution, and phenotypic impact of new genes. (2010, positive): “This process was dubbed ‘‘subfunctionalization’’ and may be shaped by natural selection or involve purely neutral processes (Force et al. 1999; Conant and Wolfe 2008; Innan and Kondrashov 2010).”
Adaptive laboratory evolution – principles and applications for biotechnology (2013, background): “Whereas there is an ongoing debate about the long-term fixation of gene duplications, either by their selective advantage under selection pressure, or by selective neutrality and fixation by random drift, they are a prerequisite for the development of novel molecular functions [129-131].”
PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools (2018, background): “Because of the importance of gene duplication in creating functional diversity within a family (6,7), PANTHER defines subfamilies in terms of gene duplication events.”
Evolution of Gene Duplication in Plants1[OPEN] (2016, background): “Models for duplicate gene retention in general have been reviewed elsewhere (Innan and Kondrashov, 2010; Maere and Van de Peer, 2010); here, we will focus on examples of duplicate retention in plants (Fig.”
Whole-genome duplication in teleost fishes and its evolutionary consequences (2014, background): “Whether this model is able to explain a substantial fraction of retained paralogues depends on two factors: The abundance of multifunctional genes and the abundance of situation where optimization of one function impairs another one (Innan and Kondrashov 2010).”
Network analysis of the MVA and MEP pathways for isoprenoid synthesis. (2013, background): “Such paralogs may retain different subsets of the ancestral gene function, for example, activity during specific stages of development, in particular tissues, and/or under certain conditions (58).”