Shared principles in NF-kappaB signaling.

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Targets of curcumin (2011, background): “essential role in regulating the expression of a wide range of genes critical for innate and adaptive immunity, inflammation and cell survival [37,38].”
Transcription Factors in Long-Term Memory and Synaptic Plasticity (2009, neutral): “I Bs act by masking nuclear localization signals (NLS) within NF B subunits (88).”
Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation. (2009, methodology): “The activity of NF-kB proteins is regulated by a variety of external stimuli, including bacterial lipopolysaccharide (LPS), tumor necrosis factor-a (TNF-a) and interleukin1 (IL-1) (Hayden and Ghosh, 2008).”
IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer (2010, background): “This recruits IKKα heterodimers, which phosphorylate additional residues in the N and C termini of NF-κB2, leading to the ubiquitylation and proteasome-mediated processing of NF-κB2 to its mature form, p52 (Ref”
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. (2010, neutral): “…inflammatory gene expression, an obvious prediction is that they should be enriched for binding sites for stimulus-activated TFs required for the deployment of the inflammatory gene expression program, like NF-kB (Rel) and IRF family members (Taniguchi et al., 2001; Hayden and Ghosh, 2008).”