The Involvement of the Anterior Cingulate Cortex in Remote Contextual Fear Memory

By Paul W. Frankland, B. Bontempi, L. Talton, L. Kaczmarek, Alcino J. Silva. 2004

937 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Molecular Biology

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Citations in the corpus

FearNet: Brain-Inspired Model for Incremental Learning (2017, background): “FearNet is heavily inspired by the dual-memory model of mammalian memory (McClelland et al., 1995), which has considerable experimental support from neuroscience (Frankland et al., 2004; Takashima et al., 2006; Kitamura et al., 2017; Bontempi et al., 1999; Taupin & Gage, 2002; Gais et al., 2007).”
Calmodulin-Kinases: Modulators of Neuronal Development and Plasticity (2008, neutral): “…null mutants revealed normal hippocampal activation (i.e., immediate-early gene expression) immediately after training and following a retrieval test 24 hr later, they failed to activate cortical networks required for remote memory retrieval (i.e., 36 days after training) (Frankland et al., 2004).”
Dynamics of Hippocampal and Cortical Activation during Consolidation of a Nonspatial Memory (2006, background): “Similarly, Frankland et al. (2004) reported increases in activation of the anterior cingulate, infralimbic, prelimbic, and temporal cortices and decreases in CA1 activation during expression of contextual fear memory over 5 weeks.”
Adult neurogenesis modulates the hippocampus-dependent period of associative fear memory. (2009, background): “In rats and mice, some forms of associative and spatial memories follow a similar decay process (Anagnostaras et al., 2001; Frankland et al., 2004, 2007; Kim and Fanselow, 1992; Maviel et al., 2004; Takehara et al., 2003; Winocur, 1990).”
Memory engrams: Recalling the past and imagining the future (2020, background): “At more remote times, cortical areas, including anterior cingulate cortex or medial prefrontal cortex (mPFC), become preferentially engaged (100).”
Are The Dorsal and Ventral Hippocampus functionally distinct structures? (2010, background): “…2006; Roberts et al., 2007)—two cortical regions involved primarily in the cognitive processing of visuospatial information and memory processing (Frankland et al., 2004; Han et al., 2003; Jones and Wilson, 2005; Lavenex et al., 2006) and environmental exploration (spatial navigation) in rats…”
Using immediate-early genes to map hippocampal subregional functions. (2007, background): “Interaction of Arc with microtubule associated protein 2 (MAP2) was suggested to play a role in cytoskeleton destabilization in studies of transfected primary neurons (Fujimoto et al. 2004).”
The hippocampus and related neocortical structures in memory transformation. (2018, background): “Early inactivation of the mPFC does not impact memory retrieval (but see 142), but if the reorganized remote memory network is allowed to develop, later inactivation of the mPFC impairs subsequent memory retrieval [73,84,156].”
Persistence of long-term memory storage requires a late protein synthesis- and BDNF- dependent phase in the hippocampus. (2007, neutral): “Recent studies have started to address this issue of memory persistence, focusing mainly on the neocortex as the region of permanent memory storage (Bontempi et al., 1999; Burwell et al., 2004; Frankland et al., 2004; Maviel et al., 2004).”