NMDA receptor subunits: diversity, development and disease.

By S. Cull-Candy, S. Brickley, M. Farrant. Current Opinion in Neurobiology, 2001

1,778 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/9c99171e8a4c2e6e741b10663298f4d91251dfe1

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In Cellular and Molecular Neuroscience

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Citations in the corpus

The Role of N-Methyl-d-Aspartate (NMDA) Receptors in Pain: A Review (2003, background): “Of note, NR1/NR2C heteromers have a much longer deactivation time, lower conductance, higher affinity for glutamate, and weaker magnesium block than NR1/NR2A receptors, but they have comparable calcium permeability (7).”
Differential Roles of NR2A and NR2B-Containing NMDA Receptors in Cortical Long-Term Potentiation and Long-Term Depression (2004, background): “…this remains a matter of speculation, one possible explanation is that NR2A-containing and NR2B-containing NMDAR EPSCs by virtue of their different kinetics (Cull-Candy et al., 2001) provide the different levels of intracellular calcium required for LTP and LTD (Lisman, 1989, Cho et al., 2001).”
Regulation of NMDA Receptor Subunit Expression and Its Implications for LTD, LTP, and Metaplasticity (2008, background): “Additional heterogeneity of NMDAR functions can arise through alternative splicing (reviewed in Cull-Candy et al., 2001).”
NMDA receptors, place cells and hippocampal spatial memory (2004, background): “Among the seven identified subunits (NR1, NR2A–D, and NR3A and B), the NR1 subunit is the only one that is indispensable for the formation of a functional receptor; its elimination would abolish all functional NMDARs in a cel”
General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal (2008, neutral): “Postsynaptic receptors at glutamatergic synapses fall into two broad categories: NMDA ( N -methyl- D -aspartate) receptors and non-NMDA receptor”
Distinct Roles of NR2A and NR2B Cytoplasmic Tails in Long-Term (2010, neutral): “NMDARs are tetramers composed of two NR1 subunits plus two NR2 subunits, of which there are four kinds encoded by distinct genes: NR2A, NR2B, NR2C, and NR2D (Cull-Candy et al., 2001).”
Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits (2002, background): “jpg" NDATA ITEM> ]> The N -methyl- d -aspartate subtype of glutamate receptor (NMDAR) serves critical functions in physiological and pathological processes in the central nervous system, including neuronal development, plasticity and neurodegeneratio”
The amygdaloid complex: anatomy and physiology. (2003, background): “Native NMDA receptors are thought to be heteromultimers containing four or five subunits consisting of two NR1 subunits and two or three NR2 subunits (38).”
Astrocyte control of synaptic transmission and neurovascular coupling. (2006, background): “Studies in which the different NMDAR subunits are expressed in heterologous systems have shown that certain subunit combinations have distinguishing kinetic properties (41, 111, 133, 218).”