Cathelicidins, multifunctional peptides of the innate immunity

By M. Zanetti. Journal of Leukocyte Biology, 2004

1,057 citations recorded by the source corpus.

Subfields: Immunology, Microbiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/9beee4a98d7f902cfdf3806d0a4d82995005d60c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. Yong‐jun Liu
2. M. Gilliet
3. H. Kono
4. H. Jenssen
5. P. Hamill
6. K. Rock
7. M. Malmsten
8. A. Schmidtchen

In Microbiology

1. Robert E. W. Hancock
2. M. Malmsten
3. A. Schmidtchen
4. Mukesh Pasupuleti
5. H. Jenssen
6. P. Hamill
7. Vienna Mackey
8. A. Ouellette

In Molecular Biology

1. M. Malmsten
2. A. Schmidtchen
3. Mukesh Pasupuleti
4. Robert E. W. Hancock
5. H. Jenssen
6. H. Kono
7. K. Rock
8. A. Ouellette

Citations in the corpus

• Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA–Peptide Complexes in Systemic Lupus Erythematosus (2011, background): “We have recently found that in psoriasis, self-DNA becomes immunogenic and triggers TLR9 in pDCs by forming a complex with an antimicrobial peptide LL37 (22, 23) overexpressed in the skin of these patients (24).”
• The immunology of sepsis (2008, background): “Surfactants containing antibacterial substances such as cathelicidins and defensins can destroy both Gram-positive and Gramnegative pathogens via pore-forming activity [13–15].”
• The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection (2006, background): “Two main families of antimicrobial peptides in mammals, the defensins and the cathelicidins, are expressed in immune cells and at epithelial surface”
• Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea (2007, neutral): “dtd" [ ]> Cathelicidins have been identified in mammal”
• Mammalian defensins in the antimicrobial immune response (2005, background): “For mammals, there are two main genetic categories for antimicrobial peptides: cathelicidin”
• Role of intestinal microbiota and metabolites on gut homeostasis and human diseases (2017, background): “Cathelicidin LL-37, a cationic peptide with wide-spectrum antimicrobial activities, is chemotactic for neutrophils, mast cells, monocytes, and T cells [29].”
• The antimicrobial peptides and their potential clinical applications. (2019, background): “The peptide LL37, one of the mammal AMPs, is an endogenous antibiotic and the only one of the cathelicidin family discovered in human beings (Figure 1) [3, 7, 24].”
• The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide (2010, neutral): “The pleiotropic LL-37 peptide is a widely expressed archetypal AMP [10].”
• The inflammatory response to cell death. (2008, background): “In some cells these proteins can be actively secreted; (iv) Antimicrobial peptides such as cathelicidins and defensins have chemotactic activity for leukocytes in vitro (54-56); (v) Various purines such as adenosine and ATP.”