Cdx1 and cdx2 expression during intestinal development.

By D. Silberg, Gary P. Swain, E. Suh, P. Traber. Gastroenterology, 2000

620 citations recorded by the source corpus.

Subfields: Genetics, Nutrition and Dietetics, Oncology

View Paper: https://www.semanticscholar.org/paper/9b4f4c8571f9e4e53fceacbbc3bb107c21bdc74b

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In Genetics

1. Hans Clevers
2. M. van de Wetering
3. Janet Rossant
4. Nick Barker
5. R. Nusse
6. Pengfei Lu

In Oncology

1. Hans Clevers
2. M. van de Wetering
3. Nick Barker
4. Pengfei Lu

Citations in the corpus

• Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst (2005, positive): “…2001) 1:500-1:1000 of 0.6 mg immunoglobulin/ml [specificity of anti-Cdx2 CNL was confirmed in blocking experiments as described by Silberg et al. (Silberg et al., 2000)]; monoclonal anti-Cdx2 (CDX2-88, BioGenex, CA, USA) 1:200; monoclonal mouse anti-Oct4 (C10; Santa Cruz Biotechnology) 1:100;…”
• SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes (2004, background): “In the intestinal epithelium, the CDX1 transcription factor is mostly expressed in the crypts whereas CDX2 is mostly active on the villi (Subramanian et al., 1998; Silberg et al., 2000).”