Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL.

By T. Vaisar, S. Pennathur, P. Green, Sina A. Gharib, A. Hoofnagle, M. Cheung, Jaeman Byun, Simona Vuletic, S. Kassim, Pragya Singh and 11 more. Journal of Clinical Investigation, 2007

973 citations recorded by the source corpus.

Subfields: Cancer Research, Hematology, Immunology

View Paper: https://www.semanticscholar.org/paper/24022b6a7422b6b08cc20b4e0a6d096b4ed41d7c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Peter Libby
2. G. Hansson
3. P. Ridker

In Hematology

1. P. Ridker

In Immunology

1. Peter Libby
2. P. Ridker
3. G. Hansson
4. I. Tabas
5. Jongsoon Lee
6. Byung-Cheol Lee
7. V. Z. Rocha
8. K. Bornfeldt

Citations in the corpus

• HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms (2011, methodology): “With the use of mass-spectrometry-based proteomics, Vaisar and colleagues identified 48 different proteins in HDL isolated from healthy individuals and patients with CHD”
• Cholesterol efflux and atheroprotection: Advancing the concept of reverse cholesterol transport (2012, background): “This suggests that the term “HDL” refers to a constellation of distinct protein and lipid constructs that share a similar density (20,21), but may vary widely in function (22), as originally suggested by Alaupovic and colleagues (23).”
• Progress and challenges in translating the biology of atherosclerosis (2011, background): “HDL particles associate with dozens of proteins, many with biological activities that have relevance to atherogenesi”
• Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts (2008, background): “The 50-nm amine-modified particles have the highest number of detected apolipoproteins, 9 of the 10 identified being associated with HDL, suggesting that 50-nm amine-modified particles associate with HDL. Apolipoprotein B-100 (the major protein in VLDL and LDL particles, but not HDL) (16) is associa”