The journey of a drug-carrier in the body: an anatomo-physiological perspective.

By N. Bertrand, J. Leroux. Journal of Controlled Release, 2012

647 citations recorded by the source corpus.

Subfields: Biomaterials, Molecular Biology, Pharmaceutical Science

View Paper: https://www.semanticscholar.org/paper/9913a9c652816e413aa37068617b06317d66077f

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In Biomaterials

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In Pharmaceutical Science

N. Bertrand

Citations in the corpus

Interactions of nanomaterials and biological systems: implications to personalized nanomedicine (2012, background): “administered systemically, the proteins that adhere to their surface will greatly affect their circulation and biodistribution [22, 23].”
Nanoparticle-liver interactions: Cellular uptake and hepatobiliary elimination. (2016, background): “Mechanical properties (especially elasticity and deformability) of nanoparticles can also influence the efficiency of phagocytosis and blood circulation times [11].”
Nano-Strategies to Fight Multidrug Resistant Bacteria—“A Battle of the Titans” (2018, methodology): “…assays and protocols to assist easy comparison of data originating from in vitro and in vivo studies, for the evaluation of theirmetabolism andmode of action (Duncan and Gaspar, 2011; Bertrand and Leroux, 2012; Beyth et al., 2015; Cordeiro et al., 2016; Rai M. et al., 2016; Zazo et al., 2016).”
Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. (2014, background): “Nevertheless, this Phase 1 clinical trial did not focus on how the different MPS functions in the tumor correlate with the efficacy of the NPs.”
Impact of Particle Size and Polydispersity Index on the Clinical Applications of Lipidic Nanocarrier Systems (2018, background): “Nanocarriers circulating in normal blood vessels do not easily leave the capillaries that perfuse tissues such as the kidney, lung and heart if they have a diameter range of 100–150 nm [18,22].”