Modulation of transmitter release via presynaptic cannabinoid receptors.

By E. Schlicker, M. Kathmann. TIPS - Trends in Pharmacological Sciences, 2001

676 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Pharmacology

View Paper: https://www.semanticscholar.org/paper/98486250ba592df6bfc3562f3da919978606d4ce

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. R. Pertwee
2. K. Mackie
3. Daniele Piomelli
4. P. Castillo
5. R. Mechoulam
6. Y. Hashimotodani
7. Allyn C. Howlett
8. L. Iversen

In Cognitive Neuroscience

1. R. Pertwee
2. K. Mackie
3. P. Castillo
4. L. Iversen
5. Daniele Piomelli
6. R. Mechoulam

In Pharmacology

1. R. Pertwee
2. K. Mackie
3. Daniele Piomelli
4. R. Mechoulam
5. P. Castillo
6. Allyn C. Howlett
7. Y. Hashimotodani
8. L. Iversen

Citations in the corpus

• Cannabis and the brain. (2003, background): “…of voltage-dependent Ca2+ channels, since a number of studies have shown that cannabinoids reduce the frequencies of miniature excitatory or inhibitory synaptic currents, which are Ca2+ independent, rather than altering their amplitude, which is Ca2+ sensitive (Schlicker and Kathmann, 2001).”
• The endocannabinoid system and its therapeutic exploitation (2004, neutral): “In the CNS and PNS, the preferential (although not exclusive) distribution of CB 1 receptors at presynaptic neurons, their coupling to the inhibition of voltage-activated Ca 2+ channels, and the stimulation of endocannabinoid formation by increased intracellular Ca 2+ and activation of other GPCR”
• International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors (2002, background): “The CB 1 receptors are located on prejunctional neurons and mediate inhibition of electrically evoked contractile transmitter release (Coutts and Pertwee, 1997; Pertwee, 1997; Schlicker and Kathmann, 2001).”
• The molecular logic of endocannabinoid signalling (2003, background): “Other neurotransmitters The ability of cannabinoid agonists to inhibit the release of neurotransmitters in the CNS is not restricted to glutamate and GAB”
• Endocannabinoid signaling and synaptic function (2012, background): “Review and GABA, CB 1 Rs can also control the release of several neuromodulators including serotonin, acetylcholine, dopamine, opioids, norepinephrine, and cholecystokinin (Alger, 2002; Kano et al., 2009; Schlicker and Kathmann, 2001).”
• Endocannabinoids Mediate Rapid Retrograde Signaling At Interneuron → Pyramidal Neuron Synapses of the Neocortex (2003, background): “Second, activation of CB1R re- duces neocortical GABA levels (Ferraro et al. 2001) by inhibiting Ca2 -dependent GABA release (Trettel and Levine 2002), consistent with the effects of CB1R agonists in other brain regions (reviewed by Schlicker and Kathmann 2001).”