Mitochondrial reactive oxygen species in cell death signaling.

By C. Fleury, B. Mignotte, J. Vayssiere. Biochimie, 2002

1,054 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/976f6900edc48883e45cf87c203b3e586e6bf993

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Citations in the corpus

IMMUNE TOLERANCE INDUCTION BY APOPTOTIC CELLS REQUIRES CASPASE-DEPENDENT OXIDATION OF HMGB1 (2008, background): “These toxic compounds are normally detoxified by the cell; however, during apoptosis ROS produced in the mitochondria participate in the apoptotic process (Fleury et al., 2002).”
Cadmium stress: an oxidative challenge (2010, positive): “Both apoptosis and necrosis can be induced by increased accumulation of ROS (Fleury et al. 2002; Hossain et al. 2009), and increased lipid peroxidation after Cd-exposure has been shown several times (Hussain et al. 1987; Yiin et al. 2000; Jurczuk et al. 2004; Babu et al. 2006; Kotelnikova et al.…”
Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells (2008, background): “It is known that ROS generation is associated with apoptosis.(20,23) We hypothesize that ROS are the trigger for autophagy and autophagic cell death.”
Calcium, ATP, and ROS: a mitochondrial love-hate triangle. (2004, background): “These ROS can damage cellular components such as proteins, lipids, and DNA (70), but recent evidence also highlights a specific role in redox cell signaling for mitochondrial ROS (55, 203).”
Cellular Stress Responses: Cell Survival and Cell Death (2010, background): “Oxidative damage mediated by free radicals is a contributing factor to ischemia/reperfusion-induced injury in cardiomyocytes [275–278].”
Invited Review: Oxidation of Biological Systems: Oxidative Stress Phenomena, Antioxidants, Redox Reactions, and Methods for Their Quantification (2002, background): “The reduction of oxygen to water in the mitochondria for ATP production occurs through the donation of 4 electrons to oxygen to produce water (69).”
Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. (2006, background): “The reaction of the renegade electron with molecular oxygen produces an oxygen radical, which is normally converted into H2O2 or other ROS, including hydroxyl radicals and superoxide anions, before being eliminated [73].”
Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy. (2008, background): “[58] C.”