Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells.
By M. Guzman, S. Neering, D. Upchurch, B. Grimes, D. Howard, D. Rizzieri, S. Luger, C. Jordan. Blood, 2001
739 citations recorded by the source corpus.
Subfields: Cancer Research, Hematology, Immunology
View Paper: https://www.semanticscholar.org/paper/96842f8c99e7af018667dc9ff12e358fdc3de39a
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Citations in the corpus
- Transient Low Doses of DNA Demethylating Agents Exert Durable Anti-tumor Effects on Hematological and Epithelial Tumor Cells (2012, result): “Ara-C, again, fails to reduce LTC-IC (Figure 1E), which is consistent with the known poor capability of this drug to target such leukemic cell populations (Guzman et al., 2001).”
- Targeting of CD44 eradicates human acute myeloid leukemic stem cells (2006, background): “Many studies have reported that AML LSCs are quiescent or slowly dividing, whereas clonogenic progenitors are rapidly proliferatin”
- Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity (2004, background): “However these marking studies were unsuccessful (data not shown) because of poor SL-IC survival in the culture conditions required to initiate cell cycling of quiescent SL-IC”